What is the NOAEL for Silver oxide (Ag2O)?
Silver oxide (Ag2O) has 5 NOAEL studies in the database. The lowest reported value is 0.107 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Silver oxide (Ag2O)
Also known as: Argentous oxide, Disilver monoxide, Disilver oxide, Silver oxide, Silver(I) oxide (+1 more)
CAS 20667-12-3
Silver oxide (Ag2O) (CAS 20667-12-3) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Silver oxide (Ag2O) is classified GHS Danger (H271, H272, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Silver oxide (Ag2O)
CAS Number
20667-12-3
DTXSID
DTXSID40893897
Molecular Formula
2Ag.O
InChI Key
KHJDQHIZCZTCAE-UHFFFAOYSA-N
Monoisotopic Mass
229.805098
Synonyms
Argentous oxideDisilver monoxideDisilver oxideSilver oxideSilver(I) oxideEINECS No.: 243-957-1
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
BiocideSurface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.107 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 897WUN6G6T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 897WUN6G6T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 897WUN6G6T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 897WUN6G6T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disilver oxide | 243-957-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
22
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Silver oxide (Ag2O)?
Silver oxide (Ag2O) appears on 1 regulatory/inventory list including active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is Silver oxide (Ag2O) used in cosmetics?
Yes, Silver oxide (Ag2O) is also indexed as a cosmetic ingredient under the name Silver Hydroxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Silver oxide (Ag2O) come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Silver oxide (Ag2O) have different safety status in cosmetics vs industrial chemicals?
Silver oxide (Ag2O) is classified GHS Danger (H271, H272, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Is Silver oxide (Ag2O) used outside industrial chemicals?
Silver oxide (Ag2O) also appears in cosmetics, pharmaceutical databases.