Is Salvianolic Acid B safe in cosmetics?
Salvianolic Acid B has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Salvianolic Acid B
Also known as: 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-, 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-, 3-Benzofurancarboxylic acid, 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, [2S-[2α,3β(S*),4[E(S*)]]]-, Dan Shen Suan B, Danfensuan B (+4 more)
INCI: SALVIANOLIC ACID B (NOT UNIVERSALLY LISTED IN COSING AS A STANDARD COSMETIC INCI; MAY BE LISTED AS A COMPONENT OF SALVIA MILTIORRHIZA ROOT EXTRACT)
Salvianolic Acid B (CAS 121521-90-2) is a cosmetic cosmetic ingredient functioning as Antioxidant, anti-inflammatory (primarily pharmaceutical/nutraceutical use;. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 121521-90-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, anti-inflammatory (primarily pharmaceutical/nutraceutical use; emerging cosmetic active)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2R)-2-[(E)-3-[(2S,3S)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoic acid
InChIKey
SNKFFCBZYFGCQN-VWUOOIFGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated; no GRAS status. Permitted as a cosmetic ingredient under general safety provisions if adequate safety data exist
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Salvianolic Acid B.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Salvianolic Acid B.
Known Synonyms
3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-
3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-
3-Benzofurancarboxylic acid, 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, [2S-[2α,3β(S*),4[E(S*)]]]-
Dan Shen Suan B
Danfensuan B
Lithospermate B
Salvianolate
ZINC 49538628
UNII-C1GQ844199
Chemical Function
Humectant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1615434
Frequently Asked Questions
Is Salvianolic Acid B allowed in the EU?
Salvianolic Acid B EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Salvianolic Acid B do in cosmetics?
Salvianolic Acid B functions as: Antioxidant, anti-inflammatory (primarily pharmaceutical/nutraceutical use; emerging cosmetic active). It is classified as a cosmetic ingredient in our database. CAS number: 121521-90-2.
Is Salvianolic Acid B used outside cosmetics?
Salvianolic Acid B also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Salvianolic Acid B compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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