NOAEL Data Cosmetic Ingredient

Lithospermic acid B

Also known as: 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-, 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-, 3-Benzofurancarboxylic acid, 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, [2S-[2α,3β(S*),4[E(S*)]]]-, Dan Shen Suan B, Danfensuan B (+5 more)

CAS 121521-90-2

Lithospermic acid B (CAS 121521-90-2) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Salvianolic Acid B →

SOURCE NOAEL studies
NOAEL studies
5
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
Lithospermic acid B
CAS Number
121521-90-2
DTXSID
DTXSID201031347
Molecular Formula
C36H30O16
InChI Key
SNKFFCBZYFGCQN-VWUOOIFGSA-N
Monoisotopic Mass
718.153385
Synonyms
3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-3-Benzofurancarboxylic acid, 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, [2S-[2α,3β(S*),4[E(S*)]]]-Dan Shen Suan BDanfensuan BLithospermate BSalvianolateSalvianolic acid BZINC 49538628UNII-C1GQ844199

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
HumectantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
C1GQ844199UNIIFDA UNII substance identifier--openFDA substances
C1GQ844199UNIIFDA UNII substance identifier--openFDA substances
C1GQ844199UNIIFDA UNII substance identifier--openFDA substances
C1GQ844199UNIIFDA UNII substance identifier--openFDA substances
0.08fractionFu-HumanNTP ICE adme parameters

Showing 5 of 5 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed CHEMBL1615434
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Lithospermic acid B?

Lithospermic acid B has 5 NOAEL studies in the database. The lowest reported value is C1GQ844199 UNII. Source: openFDA substances.

Is Lithospermic acid B used in cosmetics?

Yes, Lithospermic acid B is also indexed as a cosmetic ingredient under the name Salvianolic Acid B. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Lithospermic acid B come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Lithospermic acid B used outside industrial chemicals?

Lithospermic acid B also appears in cosmetics, pharmaceutical databases.