Is Repagermanium safe in cosmetics?
Repagermanium has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted.
Good
Cosmetic Ingredient
Repagermanium
Also known as: Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-, Propagermanium, Bis-beta-carboxyethylgermanium sesquioxide, BRN 4141883, 2-Carboxyethylgermasesquioxane (+14 more)
INCI: REPAGERMANIUM
Repagermanium (CAS 12758-40-6) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 12758-40-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid
InChIKey
XEABSBMNTNXEJM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not specifically restricted; permitted under general cosmetic ingredient provisions; used in marketed products (Dr. Jart+, numbuzin)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Repagermanium.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Repagermanium.
Known Synonyms
Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-
Propagermanium
Bis-beta-carboxyethylgermanium sesquioxide
BRN 4141883
2-Carboxyethylgermasesquioxane
Carboxylethylgermanium sesquioxide
3,3'-(Dioxodigermoxanylene) dipropanoic acid
Dipropanoic acid germanium sequioxide
EINECS 235-800-0
3,3'-(Germanoic anhydride) dipropanoic acid
NSC 267004
Propanoic acid, 3,3'-(oxybis(oxogermylene))bis-
Propionic acid, 3,3'-(1,3-dioxodigermoxanylene)di-
14C-Proxigermanium
UNII-1Q2P9TO9Q7
3,3'-(1,3-dioxo-1,3-digermoxanediyl)dipropionic acid
Proxigermanium
carboxyethylgermanium sesquioxide
2-(Carboxyethyl)germanium sesquioxide
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
pharmaceutical
pharmaceutical
Frequently Asked Questions
Is Repagermanium allowed in the EU?
Repagermanium EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Repagermanium do in cosmetics?
Repagermanium functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 12758-40-6.
Is Repagermanium used outside cosmetics?
Repagermanium also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Repagermanium compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
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Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
Propagermanium
Poor
Chemical family
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RESEDA LUTEOLA EXTRACT
Good
Browse nearby
Skin Conditioning, Soothing
RESVERATROL DIMETHYL ETHER
Good
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Antioxidant, Skin Conditioning
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