NOAEL Studies Cosmetic Ingredient

Regulatory and NOAEL Studies

INCI: REGULATORY AND

CAS: 28874-51-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP ICE acute oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute oral LD50 >2000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_5064; row=8368; data_type=In Vivo; mixture=Chemical; chemical_name=Sodium pidolate; preferred_name=Sodium pidolate; dtxsid=DTXSID50183074; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID50183074; source_file=acute_oral.xlsx
ECHA 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA NOAEL =7200 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae66e4b0a7c65d1c906f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/23503/7/6/2?documentUUID=5d9841a5-57c6-4778-8771-3730f19b9c2a; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15834525:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9f64f7e37a4fa53b10af8291603e80c4
ECHA NOAEL =8200 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae66e4b0a7c65d1c906f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/23503/7/6/2?documentUUID=5d9841a5-57c6-4778-8771-3730f19b9c2a; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15834524:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6382da9d9d3ff5724d317b8440a6799f
ToxValDB GESTIS DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL systemic =141 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634858:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_23d8e85145b4b8ea42adf090ac89b54c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 1V74VH163T UNII - - - chemical {"approval_status":null,"molecular_formula":"C5H6NO3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"1V74VH163T"}
openFDA substances FDA UNII substance identifier 1V74VH163T UNII - - - chemical {"approval_status":null,"molecular_formula":"C5H6NO3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"1V74VH163T"}
openFDA substances FDA UNII substance identifier 1V74VH163T UNII - - - chemical {"approval_status":null,"molecular_formula":"C5H6NO3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"1V74VH163T"}
openFDA substances FDA UNII substance identifier 1V74VH163T UNII - - - chemical {"approval_status":null,"molecular_formula":"C5H6NO3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"1V74VH163T"}