Is Quaternium-18 Methosulfate safe in cosmetics?
Quaternium-18 Methosulfate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Quaternium-18 Methosulfate
Also known as: 1-Decanaminium, N,N-dimethyl-N-octyl-, chloride, Caswell No. 613A, N,N-Dimethyl-N-octyl-1-decanaminium chloride, EINECS 251-035-5, EPA Pesticide Chemical Code 069165 (+1 more)
INCI: QUATERNIUM-18 METHOSULFATE
Quaternium-18 Methosulfate (CAS 32426-11-2) is a cosmetic cosmetic ingredient functioning as Antistatic, Hair Conditioning, Emulsifier, Softener [^1_10]. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 32426-11-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Quaternium-18 Methosulfate is classified GHS Danger (H302, H314, H400) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic, Hair Conditioning, Emulsifier, Softener [^1_10]
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
decyl-dimethyl-octylazanium chloride
InChIKey
SCXCDVTWABNWLW-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; no specific restriction; often referenced alongside Quaternium-18 CIR data for read-across
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Quaternium-18 Methosulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Biocide
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for Quaternium-18 Methosulfate.
Known Synonyms
1-Decanaminium, N,N-dimethyl-N-octyl-, chloride
Caswell No. 613A
N,N-Dimethyl-N-octyl-1-decanaminium chloride
EINECS 251-035-5
EPA Pesticide Chemical Code 069165
UNII-0T2NG1539G
Chemical Function
Surfactant (surface active agent)
Biocide
Anti-static agent
Regulatory Lists
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Frequently Asked Questions
Is Quaternium-18 Methosulfate allowed in the EU?
Quaternium-18 Methosulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Quaternium-18 Methosulfate do in cosmetics?
Quaternium-18 Methosulfate functions as: Antistatic, Hair Conditioning, Emulsifier, Softener [^1_10]. It is classified as a cosmetic ingredient in our database. CAS number: 32426-11-2.
Is Quaternium-18 Methosulfate used outside cosmetics?
Quaternium-18 Methosulfate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Quaternium-18 Methosulfate have different safety status in cosmetics vs industrial chemicals?
Quaternium-18 Methosulfate is classified GHS Danger (H302, H314, H400) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Quaternium-18 Methosulfate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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