Is Polyglyceryl-3 Isostearate safe in cosmetics?
Polyglyceryl-3 Isostearate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Polyglyceryl-3 Isostearate
INCI: POLYGLYCERYL-3 ISOSTEARATE
Polyglyceryl-3 Isostearate (CAS 127512-63-4) is a cosmetic cosmetic ingredient functioning as Surfactant – emulsifying; skin conditioning – emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 127512-63-4 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant – emulsifying; skin conditioning – emollient
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; CIR (2016) — safe in present practices of use when formulated to be non-irritating
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-3 Isostearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsifier
{"cas_number": "Various_3_Iso", "ingredient_class": "O/W_emulsifier", "chemical_type": "polyglycerol_ester", "HLB_value": "11.5", "HLB_required_for_oil_phase": "10-14", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "2-5", "surface_tension_reduction_mN_m": "31", "interfacial_tension_reduction": "35", "foam_formation": "moderate", "foam_stability": "low", "liquid_crystal_formation": "mo…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Expert Verdict
Expert safety assessment and concern-level summary for Polyglyceryl-3 Isostearate.
Chemical Function
Emulsifier
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Frequently Asked Questions
Is Polyglyceryl-3 Isostearate allowed in the EU?
Polyglyceryl-3 Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-3 Isostearate do in cosmetics?
Polyglyceryl-3 Isostearate functions as: Surfactant – emulsifying; skin conditioning – emollient. It is classified as a cosmetic ingredient in our database. CAS number: 127512-63-4.
Compliance Tools
Check Polyglyceryl-3 Isostearate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Not Reported
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