Is Polyglyceryl-2 Sesquiisostearate safe in cosmetics?
Polyglyceryl-2 Sesquiisostearate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Emulsifier
Polyglyceryl-2 Sesquiisostearate
Also known as: Diglyceryl diisostearate, Isooctadecanoic acid, diester with oxybis(propenediol)
INCI: POLYGLYCERYL-2 SESQUIISOSTEARATE
Polyglyceryl-2 Sesquiisostearate (CAS 67938-21-0) is a cosmetic emulsifier functioning as Emulsifying (W/O). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 67938-21-0 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifying (W/O)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[2-hydroxy-3-[2-hydroxy-3-(16-methylheptadecanoyloxy)propoxy]propyl] 16-methylheptadecanoate
InChIKey
LDDUCKDUDZVHLN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
VCRP listed. CIR 2017 safe in present practices.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-2 Sesquiisostearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsion_hlb
{"hlb_value": "4.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.55-0.75", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "polyglyceryl_3_diisostearate", "optimal_oil_phase_pct": "58-82", "optimal_water_phase_pct": "18-42", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.0-10.5", "viscosi…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Expert Verdict
Expert safety assessment and concern-level summary for Polyglyceryl-2 Sesquiisostearate.
Known Synonyms
Diglyceryl diisostearate
Isooctadecanoic acid, diester with oxybis(propenediol)
Chemical Function
Emulsifier
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Polyglyceryl-2 Sesquiisostearate allowed in the EU?
Polyglyceryl-2 Sesquiisostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-2 Sesquiisostearate do in cosmetics?
Polyglyceryl-2 Sesquiisostearate functions as: Emulsifying (W/O). It is classified as a Emulsifier in our database. CAS number: 67938-21-0.
Is Polyglyceryl-2 Sesquiisostearate used outside cosmetics?
Polyglyceryl-2 Sesquiisostearate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Polyglyceryl-2 Sesquiisostearate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Polyglyceryl-2 Diisostearate
Good
Chemical family
Emulsifier, emollient
POLY 1,2-BUTANEDIOL-6 PROPYLENE GLYCOL
Good
Browse nearby
Solvent
POLY METHYL STYRENE ISOPROPANOL KETONE
Good
Browse nearby
Light Stabilizer
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