Is Polyglyceryl-2 Oleate safe in cosmetics?
Polyglyceryl-2 Oleate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Polyglyceryl-2 Oleate
INCI: POLYGLYCERYL-2 OLEATE
Polyglyceryl-2 Oleate (CAS 49553-76-6 / 9007-48-1 (generic)) is a cosmetic cosmetic ingredient functioning as Skin-conditioning agent – emollient; surfactant – emulsifying agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 49553-76-6 / 9007-48-1 (generic) →
Auto-generated CPSR Part A draft with source citations
Function
Skin-conditioning agent – emollient; surfactant – emulsifying agent
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: Safe as used (2016/2023); FDA-approved as inactive ingredient in drug products (Polyglyceryl-3 Oleate approved in topical, oral, vaginal drugs)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-2 Oleate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsifier
{"cas_number": "Various_2_Ole", "ingredient_class": "O/W_emulsifier", "chemical_type": "polyglycerol_ester", "HLB_value": "14.0", "HLB_required_for_oil_phase": "12-16", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "critical_micelle_concentration_pct": "0.01-0.05", "surface_tension_reduction_mN_m": "34", "interfacial_tension_reduction": "38", "foam_formation": "moderate", "fo…
Expert Verdict
Expert safety assessment and concern-level summary for Polyglyceryl-2 Oleate.
Frequently Asked Questions
Is Polyglyceryl-2 Oleate allowed in the EU?
Polyglyceryl-2 Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-2 Oleate do in cosmetics?
Polyglyceryl-2 Oleate functions as: Skin-conditioning agent – emollient; surfactant – emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 49553-76-6 / 9007-48-1 (generic).
Compliance Tools
Check Polyglyceryl-2 Oleate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Not Reported
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