Is Polydatin safe in cosmetics?
Polydatin has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Polydatin
INCI: POLYDATIN
Polydatin (CAS 27208-80-6 (also reported: 65914-17-2)) is a cosmetic cosmetic ingredient functioning as Antioxidant; skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 27208-80-6 (also reported: 65914-17-2) →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant; skin conditioning agent
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No CIR review; no specific FDA restriction. Widely studied as resveratrol precursor.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polydatin.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
antioxidant
{"cas_number": "27208-80-6", "antioxidant_class": "polyphenol", "chemical_subclass": "resveratrol glycoside", "molecular_weight_daltons": "390.38", "orac_value_umol_te_per_g": "13400", "dpph_radical_scavenging_ic50_ug_per_ml": "14-25", "abts_trolox_equivalent": "not available", "singlet_oxygen_quenching": "not available", "superoxide_dismutase_mimetic": "not available", "hydroxyl_radical_scavengin…
Expert Verdict
Expert safety assessment and concern-level summary for Polydatin.
Frequently Asked Questions
Is Polydatin allowed in the EU?
Polydatin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polydatin do in cosmetics?
Polydatin functions as: Antioxidant; skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 27208-80-6 (also reported: 65914-17-2).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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