Good Cosmetic Ingredient NOAEL Data

Polyacrylic Acid

Also known as: Acrylic acid, polymers, Acrylic acid homopolymer, Acrylic acid polymer, Acrylic acid resin, Poly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex (+15 more)

INCI: POLYACRYLIC ACID

Polyacrylic Acid (CAS 9003-01-4) is a cosmetic cosmetic ingredient functioning as Viscosity controlling (thickener/gelling agent); also known by trade names. Reported NOAEL =53 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 9003-01-4 →

Auto-generated CPSR Part A draft with source citations
Function
Viscosity controlling (thickener/gelling agent); also known by trade names Carbomer 934/940
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
618-347-7

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR reviewed (2002) — safe as used when formulated to avoid skin irritation

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Polyacrylic Acid.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Polyacrylic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =53 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =240 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =460 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

IARC Carcinogenicity

International Agency for Research on Cancer (WHO) monograph evaluation.

IARC Group
3
Volume
19, Sup 7
Evaluation Year
1987

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Binder Biocide Chelating agent Corrosion inhibitor Defoamer Dispersing agent Emulsifier Film former Flow promoter
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL) FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Polyacrylic Acid.

Regulatory Flags

epa_safer_alternative

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Polyacrylic Acid by CAS number or substance name.

Studies
3
Lowest NOAEL
53 mg/kg bw/day
Highest NOAEL
460 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Acrylic acid, polymers Acrylic acid homopolymer Acrylic acid polymer Acrylic acid resin Poly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex 2-Propenic acid homopolymer, Polyacrylic acid, Carboxypolymethylene Poly(acrylic acid) 2-Propenoic Acid, Polymer ACRYLIC ACID, OLIGOMERS POLYACRYLATE POLYACRYLIC ACID HOMOPOLYMER Alcosperse 409 Alcoprint PTF-Z 328 Aquatreat AR 4 Aqualic HL 415 Carboxypolymethylene Synocure 866EEP75 Three Bond 1131 Versicol E 15 Turfine P 20

Chemical Function

Dispersing agent Binder Thickening agent

Regulatory Lists

SCIL (9/2019) CEDI inert_ingredient; Pesticides Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - liniment inert_ingredient; non_food_use; Pesticides Indirect additives food contact (10/2018) Journal of Veterinary Diagnostic Investigation

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Polyacrylic Acid safe in cosmetics?

Polyacrylic Acid has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.

Is Polyacrylic Acid allowed in the EU?

Polyacrylic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyacrylic Acid do in cosmetics?

Polyacrylic Acid functions as: Viscosity controlling (thickener/gelling agent); also known by trade names Carbomer 934/940. It is classified as a cosmetic ingredient in our database. CAS number: 9003-01-4.

What is the NOAEL for Polyacrylic Acid?

The NOAEL (No Observed Adverse Effect Level) for Polyacrylic Acid is =53 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 3 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Polyacrylic Acid used outside cosmetics?

Polyacrylic Acid also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Polyacrylic Acid have different safety status in cosmetics vs industrial chemicals?

Polyacrylic Acid is classified GHS Danger (H315, H319, H335, H340, H350) in the chemicals database but is allowed in EU cosmetics.

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