Is Poloxamine 1104 safe in cosmetics?
Poloxamine 1104 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Poloxamine 1104
Also known as: Oxirane, 2-methyl-, polymer with oxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1), Oxirane, polymer with methyloxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1), Methyloxirane polymerise avec l'oxirane, ether (4:1) avec l'ethylenedinitrilotetrapropanol, Methyloxirane polymer with oxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1), EC No.: 601-047-5
Poloxamine 1104 (CAS 11111-34-5) is a cosmetic cosmetic ingredient functioning as Emulsifier; Fragrance; Surfactant (surface active agent). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 11111-34-5 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifier; Fragrance; Surfactant (surface active agent)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA monograph; no CIR assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Poloxamine 1104.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Fragrance
Surfactant (surface active agent)
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Poloxamine 1104.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Oxirane, 2-methyl-, polymer with oxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1)
Oxirane, polymer with methyloxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1)
Methyloxirane polymerise avec l'oxirane, ether (4:1) avec l'ethylenedinitrilotetrapropanol
Methyloxirane polymer with oxirane, ether with (1,2-ethanediyldinitrilo)tetrakis[propanol] (4:1)
EC No.: 601-047-5
Chemical Function
Surfactant (surface active agent)
Emulsifier
Regulatory Lists
IFRA Transparency
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Poloxamine 1104 allowed in the EU?
Poloxamine 1104 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamine 1104 do in cosmetics?
Poloxamine 1104 functions as: Emulsifier; Fragrance; Surfactant (surface active agent). It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.
Compliance Tools
Check Poloxamine 1104 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Alpha-Glucan Oligosaccharide-1
Excellent
Same category
Skin conditioning, cleansing, smoothi...
Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer
Excellent
Same category
Dispersing agent (nonsurfactant), vis...
Ammonium Cocoyl Isethionate
Excellent
Same category
Surfactant – cleansing, foaming
Ammonium Lauryl Sulfosuccinate
Excellent
Same category
Cleansing, foaming, surfactant
Ammonium Stearate
Excellent
Same category
Cleansing, surfactant, emulsifying
Apricot Kernel Oil Polyglyceryl-10 Esters
Excellent
Same category
Skin conditioning, emollient, surfact...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
Poloxamine 1101
Moderate
Chemical family
Surfactant – Cleansing; Surfactant – ...
Poloxamine 1102
Moderate
Chemical family
Surfactant – Cleansing; Surfactant – ...
Poloxamine 1301
Moderate
Chemical family
Surfactant – Cleansing; Surfactant – ...
Is Poloxamine 1104 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Poloxamine 1104 in your formulation.