Is Phthalimidoperoxycaproic Acid (PAP) safe in cosmetics?
Phthalimidoperoxycaproic Acid (PAP) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Phthalimidoperoxycaproic Acid (PAP)
Also known as: UNII-5OEJ6FAL6C, epsilon-(Phthalimidoperoxy)hexanoic acid, 2H-Isoindole-2-hexaneperoxoic acid, 1,3-dihydro-1,3-dioxo-, 5-(Phthalimido)percaproic acid, 6-(Phthalimidoperoxy)hexanoic acid (+2 more)
INCI: PHTHALIMIDOPEROXYCAPROIC ACID
Phthalimidoperoxycaproic Acid (PAP) (CAS 128275-31-0) is a cosmetic cosmetic ingredient functioning as Oxidising agent that changes the chemical nature of another substance by adding. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 128275-31-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Phthalimidoperoxycaproic Acid (PAP) is classified GHS Danger (H242, H318, H400) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Oxidising agent that changes the chemical nature of another substance by adding oxygen or removing hydrogen
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
6-(1,3-dioxoisoindol-2-yl)hexaneperoxoic acid
InChIKey
UZJGVXSQDRSSHU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA — not specifically restricted; permitted as a cosmetic ingredient under general cosmetic provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phthalimidoperoxycaproic Acid (PAP).
Calculate MoS for your specific formulation with the MoS Calculator.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
FlammableCorrosiveEnvironmental Hazard
Hazard Class and Category
Org. Perox. D; Eye Dam. 1; Aquatic Acute 1
Hazard Statements
- H242
- H318 Causes serious eye damage
- H400 Very toxic to aquatic life
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Oxidizing agent
Expert Verdict
Expert safety assessment and concern-level summary for Phthalimidoperoxycaproic Acid (PAP).
Known Synonyms
UNII-5OEJ6FAL6C
epsilon-(Phthalimidoperoxy)hexanoic acid
2H-Isoindole-2-hexaneperoxoic acid, 1,3-dihydro-1,3-dioxo-
5-(Phthalimido)percaproic acid
6-(Phthalimidoperoxy)hexanoic acid
6-Phthalimidohexaneperoxoic acid
Eureco HC
Chemical Function
Oxidizing agent
Regulatory Lists
active_ingredient; Europe; Pesticides
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Europe; Personal care - oral and dental care - teeth whitener
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. These obligations are: 1. If the assessment report about the chemical recommends secondary notification of the chemical in particular circumstances and any of the circumstances occur in relation to the introduction (importation or manufacture) of the chemical by a person, then the...
Frequently Asked Questions
Is Phthalimidoperoxycaproic Acid (PAP) allowed in the EU?
Phthalimidoperoxycaproic Acid (PAP) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phthalimidoperoxycaproic Acid (PAP) do in cosmetics?
Phthalimidoperoxycaproic Acid (PAP) functions as: Oxidising agent that changes the chemical nature of another substance by adding oxygen or removing hydrogen. It is classified as a cosmetic ingredient in our database. CAS number: 128275-31-0.
Is Phthalimidoperoxycaproic Acid (PAP) used outside cosmetics?
Phthalimidoperoxycaproic Acid (PAP) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Phthalimidoperoxycaproic Acid (PAP) have different safety status in cosmetics vs industrial chemicals?
Phthalimidoperoxycaproic Acid (PAP) is classified GHS Danger (H242, H318, H400) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Phthalimidoperoxycaproic Acid (PAP) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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