Is Phenolsulfonphthalein safe in cosmetics?
Phenolsulfonphthalein has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted.
Moderate
Cosmetic Ingredient
Phenolsulfonphthalein
INCI: PHENOLSULFONPHTHALEIN
Phenolsulfonphthalein (CAS 143-74-8) is a cosmetic cosmetic ingredient functioning as pH indicator, colorant (non-cosmetic primary use). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 143-74-8 →
Auto-generated CPSR Part A draft with source citations
Function
pH indicator, colorant (non-cosmetic primary use)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
InChIKey
BELBBZDIHDAJOR-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not FDA-approved as a color additive for cosmetics under 21 CFR Parts 73/74. Primarily a diagnostic/laboratory reagent.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenolsulfonphthalein.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Phenolsulfonphthalein.
Regulatory Flags
colorant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PHENOLSULFONPHTHALEIN
ChEMBL ID
CHEMBL258921
Max Phase
-1
Frequently Asked Questions
Is Phenolsulfonphthalein allowed in the EU?
Phenolsulfonphthalein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenolsulfonphthalein do in cosmetics?
Phenolsulfonphthalein functions as: pH indicator, colorant (non-cosmetic primary use). It is classified as a cosmetic ingredient in our database. CAS number: 143-74-8.
Is Phenolsulfonphthalein used outside cosmetics?
Phenolsulfonphthalein also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Phenolsulfonphthalein compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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