Is Peoniflorin safe in cosmetics?
Peoniflorin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Peoniflorin
Also known as: Paeoniae radix root, EINECS 245-476-2, beta-D-Glucopyranoside, (1aS,2R,3aR,5R,5aR,5bS)-5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta(cd)pentalen-1a(2H)-yl, Paeonia moutan, Paeony root (+1 more)
INCI: PEONIFLORIN
Peoniflorin (CAS 23180-57-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning (antioxidant / anti-inflammatory monoterpene glycoside from. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 23180-57-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning (antioxidant / anti-inflammatory monoterpene glycoside from Paeonia)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
[(1R,2S,3R,5R,6R,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl benzoate
InChIKey
YKRGDOXKVOZESV-WRJNSLSBSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not independently CIR-reviewed; falls under Paeonia family assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Peoniflorin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Peoniflorin.
Known Synonyms
Paeoniae radix root
EINECS 245-476-2
beta-D-Glucopyranoside, (1aS,2R,3aR,5R,5aR,5bS)-5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta(cd)pentalen-1a(2H)-yl
Paeonia moutan
Paeony root
UNII-21AIQ4EV64
Chemical Function
Humectant
Frequently Asked Questions
Is Peoniflorin allowed in the EU?
Peoniflorin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Peoniflorin do in cosmetics?
Peoniflorin functions as: Skin conditioning (antioxidant / anti-inflammatory monoterpene glycoside from Paeonia). It is classified as a cosmetic ingredient in our database. CAS number: 23180-57-6.
Is Peoniflorin used outside cosmetics?
Peoniflorin also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Fragrance ingredient
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Chemical family
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Binding
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