Is PEG-2 Stearamine safe in cosmetics?
PEG-2 Stearamine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
PEG-2 Stearamine
Also known as: Stearyldiethanolamine, Ethanol, 2,2'-(octadecylimino)bis-, Ethanol, 2,2'-(octadecylimino)di-, 2,2'-(Octadecylimino)bis[ethanol], Amiet 302 (+15 more)
INCI: PEG-2 STEARAMINE
PEG-2 Stearamine (CAS 10213-78-2) is a cosmetic cosmetic ingredient functioning as Emulsifying, antistatic. NOAEL 13 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 10213-78-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
PEG-2 Stearamine is classified GHS Danger (H302, H315, H318, H319, H400, H410, H412) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Emulsifying, antistatic
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-[2-hydroxyethyl(octadecyl)amino]ethanol
InChIKey
NDLNTMNRNCENRZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PEG-2 Stearamine.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for PEG-2 Stearamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =30 mg/kg bw/day | oral: gavage | Rat | subchronic | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for PEG-2 Stearamine across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Dispersing agent
Emulsifier
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for PEG-2 Stearamine.
Regulatory Flags
peg-ingredient
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-2 Stearamine by CAS number or substance name.
Studies
1
Lowest NOAEL
30 mg/kg bw/day
Highest NOAEL
30 mg/kg bw/day
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx
Known Synonyms
Stearyldiethanolamine
Ethanol, 2,2'-(octadecylimino)bis-
Ethanol, 2,2'-(octadecylimino)di-
2,2'-(Octadecylimino)bis[ethanol]
Amiet 302
Anstex SA 20
Stearylbis(hydroxyethyl)amine
Octadecyldiethanolamine
Octadecylbis(2-hydroxyethyl)amine
N-Stearyldiethanolamine
N,N-Diethanolstearylamine
N,N-Bis-β-hydroxyethyl-N-octadecylamine
N,N-Bis(β-hydroxyethyl)stearylamine
N,N-Bis(2-hydroxyethyl)stearylamine
N,N-Bis(2-hydroxyethyl)octadecylamine
N,N-Bis(2-hydroxyethyl)octadecanamine
N,N-Bis(2-hydroxyethyl)-N-octadecylamine
Hexcel 273E
Ethomeen T 18H
Electrostripper TS 2B
Chemical Function
Anti-static agent
Emulsifier
Dispersing agent
Regulatory Lists
CEDI
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-2 Stearamine allowed in the EU?
PEG-2 Stearamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-2 Stearamine do in cosmetics?
PEG-2 Stearamine functions as: Emulsifying, antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 10213-78-2.
What is the NOAEL for PEG-2 Stearamine?
The NOAEL (No Observed Adverse Effect Level) for PEG-2 Stearamine is =30 mg/kg bw/day based on a subchronic study via oral: gavage route in Rat. Source: EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx.
Is PEG-2 Stearamine used outside cosmetics?
PEG-2 Stearamine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does PEG-2 Stearamine have different safety status in cosmetics vs industrial chemicals?
PEG-2 Stearamine is classified GHS Danger (H302, H315, H318, H319, H400, H410, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check PEG-2 Stearamine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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