Is Palmitoyl Hexapeptide-14 safe in cosmetics?
Palmitoyl Hexapeptide-14 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Palmitoyl Hexapeptide-14
INCI: PALMITOYL HEXAPEPTIDE-14
Palmitoyl Hexapeptide-14 (CAS 891498-01-4) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Anti-aging, Firming, Smoothing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 891498-01-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Anti-aging, Firming, Smoothing
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexadecanamide
InChIKey
QOJFGLKMGVFTQV-AGPWLXQASA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — No FDA restriction; falls within CIR palmitoyl oligopeptide group
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Palmitoyl Hexapeptide-14.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
peptide
{"trade_name": "Lipochroman-6 component", "peptide_sequence_amino_acids": "Pal-Asp-Glu-His-Asp-Ser-Gly", "peptide_length_residues": "6", "molecular_weight_daltons": "924.0", "peptide_class": "signal", "mechanism_of_action": "Promotes epidermal turnover and skin renewal", "target_protein_or_receptor": "Keratinocyte proliferation", "collagen_boost_pct_in_vitro": "42", "elastin_stimulation": "moderat…
Expert Verdict
Expert safety assessment and concern-level summary for Palmitoyl Hexapeptide-14.
Frequently Asked Questions
Is Palmitoyl Hexapeptide-14 allowed in the EU?
Palmitoyl Hexapeptide-14 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Palmitoyl Hexapeptide-14 do in cosmetics?
Palmitoyl Hexapeptide-14 functions as: Skin Conditioning, Anti-aging, Firming, Smoothing. It is classified as a cosmetic ingredient in our database. CAS number: 891498-01-4.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Not Reported
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