Is Palmitoyl Glycine safe in cosmetics?
Palmitoyl Glycine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Palmitoyl Glycine
Also known as: N-(1-Oxohexadecyl)glycine, N-Palmitoyl glycine, UNII-M6V3RIU5KI
INCI: PALMITOYL GLYCINE
Palmitoyl Glycine (CAS 2441-41-0) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Cleansing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2441-41-0 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Cleansing
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-(hexadecanoylamino)acetic acid
InChIKey
KVTFEOAKFFQCCX-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — No FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Palmitoyl Glycine.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Softener and conditioner
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for Palmitoyl Glycine.
Known Synonyms
N-(1-Oxohexadecyl)glycine
N-Palmitoyl glycine
UNII-M6V3RIU5KI
Chemical Function
Cleaning agent
Softener and conditioner
Surfactant (surface active agent)
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PALMITOYL GLYCINE
ChEMBL ID
CHEMBL226117
Frequently Asked Questions
Is Palmitoyl Glycine allowed in the EU?
Palmitoyl Glycine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Palmitoyl Glycine do in cosmetics?
Palmitoyl Glycine functions as: Skin Conditioning, Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 2441-41-0.
Is Palmitoyl Glycine used outside cosmetics?
Palmitoyl Glycine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Palmitoyl Glycine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Not Reported
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