Is PALMATINE safe in cosmetics?
PALMATINE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
PALMATINE
Also known as: Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium, 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium, O,O-Dimethyldemethyleneberberine, Berbericinine (+12 more)
PALMATINE (CAS 3486-67-7) is a cosmetic cosmetic ingredient functioning as Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 3486-67-7 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
InChIKey
QUCQEUCGKKTEBI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory", "mechanism_of_action": "Bioactive compound, specialized mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "12", "sample_size": "35", "double_blind": "No", "placebo_controlled": "Yes", "published_journal…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for PALMATINE.
Regulatory Flags
cosing-sourced
eu-permitted
antioxidant
needs-enrichment
Known Synonyms
Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-
2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium
O,O-Dimethyldemethyleneberberine
Berbericinine
Berbinium, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-
Depiline
Fibrauretin
Fibrauretine
Huang Teng Su
5-21-06-00202
BRN 1555498
Palmatin
UNII-G50C034217
7,8,13,13a-tetrahydro-2,3,9,10-tetramethoxyberbinium
Burasaine
Calystigine
Chemical Function
Antioxidant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PALMITINE
ChEMBL ID
CHEMBL206106
Frequently Asked Questions
Is PALMATINE allowed in the EU?
PALMATINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PALMATINE do in cosmetics?
PALMATINE functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 3486-67-7.
Is PALMATINE used outside cosmetics?
PALMATINE also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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