Is Oligopeptide-68 safe in cosmetics?
Oligopeptide-68 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Oligopeptide-68
INCI: OLIGOPEPTIDE-68
Oligopeptide-68 (CAS None) is a cosmetic active ingredient functioning as Peptide / Anti-aging active. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS None →
Auto-generated CPSR Part A draft with source citations
Function
Peptide / Anti-aging active
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Oligopeptide-68.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
7 property records from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "brightening, dark-spot-reduction", "mechanism_of_action": "Inhibits tyrosinase, reduces melanin synthesis", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "0-5", "clinical_study_duration_weeks": "8", "sample_size": "40", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "JEADV", "impr…
peptide
{"cas_number": "1619994-68-1", "trade_name": "Delisens XP", "peptide_sequence_amino_acids": "Ac-Thr-Glu-Tyr", "peptide_length_residues": "3", "molecular_weight_daltons": "408.4", "peptide_class": "enzyme_inhibitor", "mechanism_of_action": "Melanogenesis inhibitor, tyrosinase and MITF inhibition", "target_protein_or_receptor": "Tyrosinase/MITF", "collagen_boost_pct_in_vitro": "0", "elastin_stimulat…
self_tanning
{"cas_number": "proprietary", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "72.0", "full_color_development_hours": "240", "color_duration_days": "14", "color_depth": "light", "undertone": "natural", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_releas…
skin_brightening
{"cas_number": "1447826-23-4", "mechanism_of_action": "Direct tyrosinase inhibition (peptide)", "melanogenesis_pathway_target": "Tyrosinase enzyme", "tyrosinase_inhibition_ic50_um": "~50-100", "tyrosinase_inhibition_vs_kojic_acid": "~1-2x weaker", "melanosome_transfer_inhibitor": "No", "melanin_oxidation_reducer": "Partial", "endothelin_pathway_blocker": "No", "alpha_msh_antagonist": "No", "clinic…
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "acceptable", "sensitive_skin": "acceptable", "combination_skin": "acceptable", "normal_skin": "acceptable", "acne_prone": "acceptable", "rosacea": "acceptable", "eczema": "acceptable", "hyperpigmentation": "recommended", "aging_mature": "acceptable", "dehydrated": "acceptable", "skin_benefit_primary": "brightening", "skin_benefit_secondary": "melanin-inhibi…
synergy
{"inci_name_2": "Tranexamic Acid", "synergy_type": "efficacy-boost", "synergy_description": "Melanin-inhibiting peptide with plasmin inhibitor for melasma", "combined_benefit": "Superior melasma treatment, comprehensive pigmentation control", "efficacy_multiplier": "2.5x", "mechanism_of_action": "Oligopeptide-68 inhibits tyrosinase; tranexamic acid blocks plasmin pathway", "optimal_ratio": "1:10 (…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "5", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Expert Verdict
Expert safety assessment and concern-level summary for Oligopeptide-68.
Frequently Asked Questions
Is Oligopeptide-68 allowed in the EU?
Oligopeptide-68 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Oligopeptide-68 do in cosmetics?
Oligopeptide-68 functions as: Peptide / Anti-aging active. It is classified as a Active Ingredient in our database. CAS number: None.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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