Good Cosmetic Ingredient NOAEL Data

Octahydro-tetramethyl-1-naphthalenol

Also known as: 1-Naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-

INCI: OCTAHYDRO-TETRAMETHYL-1-NAPHTHALENOL

Octahydro-tetramethyl-1-naphthalenol (CAS 103614-86-4) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent). Reported NOAEL =50 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 103614-86-4 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming agent)
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C14H24O
MW
208.34 g/mol
PubChem CID
20197108
IUPAC Name
2,2,6,8-tetramethyl-3,4,4a,5,8,8a-hexahydro-1H-naphthalen-1-ol
InChIKey
OEBIUKPSCOVDQZ-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Permitted — no specific CFR restriction; listed on IFRA Transparency List

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Octahydro-tetramethyl-1-naphthalenol.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Octahydro-tetramethyl-1-naphthalenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =50 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Octahydro-tetramethyl-1-naphthalenol.

Regulatory Flags

fragrance-component ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Octahydro-tetramethyl-1-naphthalenol by CAS number or substance name.

Studies
1
Lowest NOAEL
50 mg/kg bw/day
Highest NOAEL
50 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

1-Naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-

Chemical Function

Fragrance

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Octahydro-tetramethyl-1-naphthalenol safe in cosmetics?

Octahydro-tetramethyl-1-naphthalenol has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Octahydro-tetramethyl-1-naphthalenol allowed in the EU?

Octahydro-tetramethyl-1-naphthalenol EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Octahydro-tetramethyl-1-naphthalenol do in cosmetics?

Octahydro-tetramethyl-1-naphthalenol functions as: Fragrance (perfuming agent). It is classified as a cosmetic ingredient in our database. CAS number: 103614-86-4.

What is the NOAEL for Octahydro-tetramethyl-1-naphthalenol?

The NOAEL (No Observed Adverse Effect Level) for Octahydro-tetramethyl-1-naphthalenol is =50 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Octahydro-tetramethyl-1-naphthalenol used outside cosmetics?

Octahydro-tetramethyl-1-naphthalenol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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