Is NOBILETIN safe in cosmetics?
NOBILETIN has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
NOBILETIN
Also known as: NSC 76751, UNII-D65ILJ7WLY, 5,6,7,8,3',4'-Hexamethoxyflavone, Hexamethoxyflavone
NOBILETIN (CAS 478-01-3) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Antioxidant, Preservative. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical and food safety data.
View industrial chemical safety profile for CAS 478-01-3 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, Antioxidant, Preservative
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
InChIKey
MRIAQLRQZPPODS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Biocide
Preservative
Expert Verdict
Expert safety assessment and concern-level summary for NOBILETIN.
Regulatory Flags
cosing-sourced
eu-permitted
preservative
antioxidant
needs-enrichment
Known Synonyms
NSC 76751
UNII-D65ILJ7WLY
5,6,7,8,3',4'-Hexamethoxyflavone
Hexamethoxyflavone
Chemical Function
Biocide
Preservative
Antioxidant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NOBILETIN
ChEMBL ID
CHEMBL76447
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Nobiletin
Food Category
preservative
Frequently Asked Questions
Is NOBILETIN allowed in the EU?
NOBILETIN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NOBILETIN do in cosmetics?
NOBILETIN functions as: Antimicrobial, Antioxidant, Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 478-01-3.
Is NOBILETIN used outside cosmetics?
NOBILETIN also appears in pharmaceutical and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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