What is the NOAEL for Nobiletin?
Nobiletin has 4 NOAEL studies in the database. The lowest reported value is D65ILJ7WLY UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Nobiletin
Also known as: NSC 76751, UNII-D65ILJ7WLY, 5,6,7,8,3',4'-Hexamethoxyflavone, Hexamethoxyflavone
CAS 478-01-3
Nobiletin (CAS 478-01-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
0
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Nobiletin
CAS Number
478-01-3
DTXSID
DTXSID30197275
Molecular Formula
C21H22O8
InChI Key
MRIAQLRQZPPODS-UHFFFAOYSA-N
Monoisotopic Mass
402.131468
Synonyms
NSC 76751UNII-D65ILJ7WLY5,6,7,8,3',4'-HexamethoxyflavoneHexamethoxyflavone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
BiocidePreservativeAntioxidant
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| D65ILJ7WLY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D65ILJ7WLY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D65ILJ7WLY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D65ILJ7WLY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Preservatives
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
NOBILETIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Nobiletin used in cosmetics?
Yes, Nobiletin is also indexed as a cosmetic ingredient under the name NOBILETIN. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Nobiletin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Nobiletin used outside industrial chemicals?
Nobiletin also appears in cosmetics, pharmaceutical, food safety, cannabis databases.