Is NIPRADILOL safe in cosmetics?
NIPRADILOL has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
NIPRADILOL
Also known as: 2H-1-Benzopyran-3-ol, 3,4-dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, 3-nitrate, 8-{2-Hydroxy-3-[(propan-2-yl)amino]propoxy}-3,4-dihydro-2H-1-benzopyran-3-yl nitrate
NIPRADILOL (CAS 81486-22-8) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 81486-22-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydro-2H-chromen-3-yl] nitrate
InChIKey
OMCPLEZZPVJJIS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
US Notes
Regulated as a drug substance; not permitted as a cosmetic ingredient as it would trigger drug classification under the FD\&C Act
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for NIPRADILOL.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
needs-enrichment
Known Synonyms
2H-1-Benzopyran-3-ol, 3,4-dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, 3-nitrate
8-{2-Hydroxy-3-[(propan-2-yl)amino]propoxy}-3,4-dihydro-2H-1-benzopyran-3-yl nitrate
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NIPRADILOL
ChEMBL ID
CHEMBL155622
Max Phase
2
Adverse Event Associations
2
Frequently Asked Questions
Is NIPRADILOL allowed in the EU?
NIPRADILOL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NIPRADILOL do in cosmetics?
NIPRADILOL functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 81486-22-8.
Is NIPRADILOL used outside cosmetics?
NIPRADILOL also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NIPRADILOL compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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