Is Nicotiana Tabacum Leaf Extract safe in cosmetics?
Nicotiana Tabacum Leaf Extract has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Nicotiana Tabacum Leaf Extract
Also known as: Tobacco leaf, aqueous extract, Tobacco concrete, Tobacco extract, tobacco leaf injection
INCI: NICOTIANA TABACUM LEAF EXTRACT
Nicotiana Tabacum Leaf Extract (CAS 84961-66-0) is a cosmetic cosmetic ingredient functioning as Skin conditioning, Antioxidant, Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 84961-66-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Nicotiana Tabacum Leaf Extract is classified GHS Danger (H302, H310, H312, H412) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin conditioning, Antioxidant, Perfuming
Safety Rating
MODERATE
Chemistry & Identifiers
EC Number
284-656-5
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restrictions; EWG rates low concern; nicotine content in raw leaf (0.5–9%) warrants monitoring; used as skin-conditioning and perfuming agent
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Nicotiana Tabacum Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Nicotiana Tabacum Leaf Extract.
Regulatory Flags
botanical
nicotine-source
antioxidant
purity-dependent
Known Synonyms
Tobacco leaf, aqueous extract
Tobacco concrete
Tobacco extract
tobacco leaf injection
Chemical Function
Softener and conditioner
Fragrance
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Nicotiana Tabacum Leaf Extract allowed in the EU?
Nicotiana Tabacum Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Nicotiana Tabacum Leaf Extract do in cosmetics?
Nicotiana Tabacum Leaf Extract functions as: Skin conditioning, Antioxidant, Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 84961-66-0.
Is Nicotiana Tabacum Leaf Extract used outside cosmetics?
Nicotiana Tabacum Leaf Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Nicotiana Tabacum Leaf Extract have different safety status in cosmetics vs industrial chemicals?
Nicotiana Tabacum Leaf Extract is classified GHS Danger (H302, H310, H312, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Nicotiana Tabacum Leaf Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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