What is the NOAEL for Tobacco, ext.?
Tobacco, ext. has 4 NOAEL studies in the database. The lowest reported value is 3 mg/dose via oral in Rat. Source: ToxValDB_ECOTOX.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Tobacco, ext.
Also known as: Tobacco leaf, aqueous extract, Tobacco concrete, Tobacco extract, tobacco leaf injection
CAS 84961-66-0
Tobacco, ext. (CAS 84961-66-0) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Nicotiana Tabacum Leaf Extract →
Cross-Vertical Regulatory Divergence
Tobacco, ext. is classified GHS Danger (H302, H310, H312, H412) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
7 fields
Name
Tobacco, ext.
CAS Number
84961-66-0
DTXSID
DTXSID501033435
Synonyms
Tobacco leaf, aqueous extractTobacco concreteTobacco extracttobacco leaf injection
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Softener and conditionerFragrance
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3 | mg/dose | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =50 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =169 | mg/kg bw/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =244 | mg/kg bw/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tobacco, ext. | 284-656-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Botanical Extract
Frequently Asked Questions
Is Tobacco, ext. used in cosmetics?
Yes, Tobacco, ext. is also indexed as a cosmetic ingredient under the name Nicotiana Tabacum Leaf Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tobacco, ext. come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Tobacco, ext. have different safety status in cosmetics vs industrial chemicals?
Tobacco, ext. is classified GHS Danger (H302, H310, H312, H412) in the chemicals database but is allowed in EU cosmetics.
Is Tobacco, ext. used outside industrial chemicals?
Tobacco, ext. also appears in cosmetics databases.