Is MYRISTOYL SARCOSINE safe in cosmetics?
MYRISTOYL SARCOSINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
Good
Cosmetic Ingredient
MYRISTOYL SARCOSINE
Also known as: EINECS 258-007-1, N-Myristoylsarcosine acid, UNII-ZL6OI6P595
MYRISTOYL SARCOSINE (CAS 52558-73-3) is a cosmetic cosmetic ingredient functioning as Antistatic, Cleansing, Hair Conditioning, Surfactant - Cleansing. NOAEL 33.333333 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 52558-73-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
MYRISTOYL SARCOSINE is classified GHS Danger (H314, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic, Cleansing, Hair Conditioning, Surfactant - Cleansing
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-[methyl(tetradecanoyl)amino]acetic acid
InChIKey
NGOZDSMNMIRDFP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — CIR Expert Panel concluded safe as used in cosmetics when formulated to be non-irritating
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for MYRISTOYL SARCOSINE across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Cleaning agent
Softener and conditioner
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for MYRISTOYL SARCOSINE.
Regulatory Flags
cosing-sourced
eu-permitted
hair-conditioning
surfactant
needs-enrichment
Known Synonyms
EINECS 258-007-1
N-Myristoylsarcosine acid
UNII-ZL6OI6P595
Chemical Function
Surfactant (surface active agent)
Anti-static agent
Cleaning agent
Softener and conditioner
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL4462773
Frequently Asked Questions
Is MYRISTOYL SARCOSINE allowed in the EU?
MYRISTOYL SARCOSINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does MYRISTOYL SARCOSINE do in cosmetics?
MYRISTOYL SARCOSINE functions as: Antistatic, Cleansing, Hair Conditioning, Surfactant - Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 52558-73-3.
Is MYRISTOYL SARCOSINE used outside cosmetics?
MYRISTOYL SARCOSINE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does MYRISTOYL SARCOSINE have different safety status in cosmetics vs industrial chemicals?
MYRISTOYL SARCOSINE is classified GHS Danger (H314, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check MYRISTOYL SARCOSINE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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