Is MORINDA OFFICINALIS ROOT EXTRACT safe in cosmetics?
MORINDA OFFICINALIS ROOT EXTRACT has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited. 2 toxicological study endpoint(s) are available in our database.
MORINDA OFFICINALIS ROOT EXTRACT
Also known as: BRN 1915778, 1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione, 1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone, EINECS 208-315-7, UNII-H6PT94IV61
MORINDA OFFICINALIS ROOT EXTRACT (CAS 521-61-9) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Conditioning. Reported NOAEL =31 mg/kg bw in Rat (EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 521-61-9 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
InChIKey
FFWOKTFYGVYKIR-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Allowed — not listed as prohibited or restricted; subject to general cosmetic safety requirements
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for MORINDA OFFICINALIS ROOT EXTRACT. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =31 mg/kg bw | - | Rat | reproduction toxicity | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| NOAEL | =31 mg/kg bw | - | Rat | reproduction toxicity | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
Expert Verdict
Expert safety assessment and concern-level summary for MORINDA OFFICINALIS ROOT EXTRACT.
Regulatory Flags
cosing-sourced
eu-permitted
no-cas-assigned
skin-conditioning
antioxidant
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to MORINDA OFFICINALIS ROOT EXTRACT by CAS number or substance name.
Studies
2
Lowest NOAEL
31 mg/kg bw
Highest NOAEL
31 mg/kg bw
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx
Known Synonyms
BRN 1915778
1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione
1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone
EINECS 208-315-7
UNII-H6PT94IV61
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PHYSCION
ChEMBL ID
CHEMBL42624
Frequently Asked Questions
Is MORINDA OFFICINALIS ROOT EXTRACT allowed in the EU?
MORINDA OFFICINALIS ROOT EXTRACT EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does MORINDA OFFICINALIS ROOT EXTRACT do in cosmetics?
MORINDA OFFICINALIS ROOT EXTRACT functions as: Antioxidant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 521-61-9.
What is the NOAEL for MORINDA OFFICINALIS ROOT EXTRACT?
The NOAEL (No Observed Adverse Effect Level) for MORINDA OFFICINALIS ROOT EXTRACT is =31 mg/kg bw based on a reproduction toxicity study via oral route in Rat. A total of 2 study endpoints are available. Source: EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx.
Is MORINDA OFFICINALIS ROOT EXTRACT used outside cosmetics?
MORINDA OFFICINALIS ROOT EXTRACT also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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MoS Calculator
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