What is the NOAEL for Physcione?
Physcione has 6 NOAEL studies in the database. The lowest reported value is H6PT94IV61 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Physcione
Also known as: BRN 1915778, 1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione, 1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone, EINECS 208-315-7, UNII-H6PT94IV61
CAS 521-61-9
Physcione (CAS 521-61-9) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
View cosmetic safety profile for MORINDA OFFICINALIS ROOT EXTRACT →
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Physcione
CAS Number
521-61-9
DTXSID
DTXSID20200101
Molecular Formula
C16H12O5
InChI Key
FFWOKTFYGVYKIR-UHFFFAOYSA-N
Monoisotopic Mass
284.068473
Synonyms
BRN 19157781,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinoneEINECS 208-315-7UNII-H6PT94IV61
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| H6PT94IV61 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H6PT94IV61 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H6PT94IV61 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H6PT94IV61 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =31 | mg/kg bw | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| =31 | mg/kg bw | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
Showing 6 of 6 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PHYSCION
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
6
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Physcione used in cosmetics?
Yes, Physcione is also indexed as a cosmetic ingredient under the name MORINDA OFFICINALIS ROOT EXTRACT. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Physcione come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Physcione used outside industrial chemicals?
Physcione also appears in cosmetics, pharmaceutical, cannabis databases.