Is Methylfurfural safe in cosmetics?
Methylfurfural has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methylfurfural
Also known as: 5-17-09-00404, BRN 0106895, EINECS 210-622-6, FEMA No. 2702, 5-Methyl furfural (+8 more)
INCI: METHYLFURFURAL
Methylfurfural (CAS 620-02-0) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 620-02-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
5-methylfuran-2-carbaldehyde
InChIKey
OUDFNZMQXZILJD-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - no specific prohibition; FEMA GRAS 2702 for flavoring; permitted in cosmetics as a fragrance component
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methylfurfural.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1350 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
745
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
5-METHYLFURFURAL | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/37 | FAS 46-JECFA 55/137
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Degradant/impurity
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Methylfurfural.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
5-17-09-00404
BRN 0106895
EINECS 210-622-6
FEMA No. 2702
5-Methyl furfural
UNII-4482BZC72D
5-Methyl-2-furanaldehyde
5-Methyl-2-furancarbaldehyde
5-Methyl-2-furancarboxyaldehyde
5-Methyl-Furfural
FEMA 2702
Methyl-5-furfural
alpha-Methylfurfural
Chemical Function
Fragrance
Flavouring and nutrient
Degradant/impurity
Regulatory Lists
Cleaning products and household care - air freshener; Europe
air; Cleaning products and household care - air freshener; detected; emissions; Europe
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
5-METHYLFURFURAL
ChEMBL ID
CHEMBL2230304
Frequently Asked Questions
Is Methylfurfural allowed in the EU?
Methylfurfural EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methylfurfural do in cosmetics?
Methylfurfural functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 620-02-0.
Is Methylfurfural used outside cosmetics?
Methylfurfural also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methylfurfural compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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