Is Methoxyethyl Acrylate safe in cosmetics?
Methoxyethyl Acrylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methoxyethyl Acrylate
Also known as: Acrylic acid, 2-methoxyethoxy ester, Acrylic acid, 2-methoxyethyl ester, Ethylene glycol monomethyl ether acrylate, Glycol monomethyl ether acrylate, 2-Methoxyethanol, acrylate (+8 more)
INCI: METHOXYETHYL ACRYLATE
Methoxyethyl Acrylate (CAS 3121-61-7) is a cosmetic cosmetic ingredient functioning as Film forming (monomer/polymer precursor). NOAEL 13.333333 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3121-61-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Methoxyethyl Acrylate is classified GHS Danger (H226, H302, H311, H331, H314, H315, H317, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film forming (monomer/polymer precursor)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-methoxyethyl prop-2-enoate
InChIKey
HFCUBKYHMMPGBY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - no specific prohibition; acrylate monomers are common in nail and adhesive products
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methoxyethyl Acrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Methoxyethyl Acrylate across SCCS product categories, with measured dermal absorption where available.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
FlammableHealth HazardAcute ToxicityCorrosive
Hazard Class and Category
Flam. Liq. 3; Muta. 2; Repr. 1B; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1
Hazard Statements
- H226 Flammable liquid and vapour
- H341 Suspected of causing genetic defects
- H360FD
- H331 Toxic if inhaled
- H302 Harmful if swallowed
- H314 Causes severe skin burns and eye damage
- H318 Causes serious eye damage
- H317 May cause an allergic skin reaction
Specific Concentration Limits / M-factors
inhalation: ATE = 2.7 mg/L vapours; oral: ATE = 404.0 mg/kg bw
Inserted via ATP: ATP15
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1668
(EU) 2021/1902
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Film former
Expert Verdict
Expert safety assessment and concern-level summary for Methoxyethyl Acrylate.
Regulatory Flags
potential-allergen
Known Synonyms
Acrylic acid, 2-methoxyethoxy ester
Acrylic acid, 2-methoxyethyl ester
Ethylene glycol monomethyl ether acrylate
Glycol monomethyl ether acrylate
2-Methoxyethanol, acrylate
Methyl cellosolve acrylate
2-Propenioc acid, 2-methoxyethyl ester
2-Propenoic acid, 2-methoxyethyl ester
BRN 1754333
EINECS 221-499-3
NSC 24153
Sipomer MCA
UNII-515K4I683Y
Chemical Function
Film former
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Methoxyethyl Acrylate allowed in the EU?
Methoxyethyl Acrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methoxyethyl Acrylate do in cosmetics?
Methoxyethyl Acrylate functions as: Film forming (monomer/polymer precursor). It is classified as a cosmetic ingredient in our database. CAS number: 3121-61-7.
Is Methoxyethyl Acrylate used outside cosmetics?
Methoxyethyl Acrylate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Methoxyethyl Acrylate have different safety status in cosmetics vs industrial chemicals?
Methoxyethyl Acrylate is classified GHS Danger (H226, H302, H311, H331, H314, H315, H317, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Methoxyethyl Acrylate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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