Is Magnesium Nitrate safe in cosmetics?
Magnesium Nitrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Magnesium Nitrate
Also known as: Nitric acid, magnesium salt (2:1), UN 1474 (DOT), Nitric acid, magnesium salt, EINECS 233-826-7, Magnesium(II) NItrate (1:2) (+1 more)
INCI: MAGNESIUM NITRATE
Magnesium Nitrate (CAS 10377-60-3) is a cosmetic cosmetic ingredient functioning as Hair conditioning agent; stabiliser in CMIT/MIT preservative systems. NOAEL 1500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted, max 0.0015%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 10377-60-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Magnesium Nitrate is classified GHS Danger (H272, H315, H319, H335, H370, H372, H371) in the chemicals database but is allowed in EU cosmetics at max 0.0015%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair conditioning agent; stabiliser in CMIT/MIT preservative systems
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
magnesium dinitrate
InChIKey
YIXJRHPUWRPCBB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.0015%
US US Status
permitted
US Notes
Permitted — listed as indirect food additive (21 CFR §175.300, §175.320, §176.170); no cosmetic-specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Magnesium Nitrate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
May cause mechanical irritation to the eyes and respiratory tract. Ingestion could cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Magnesium Nitrate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000,000 - 10,000,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (3)
Carcinogen Classification
Ingested nitrate or nitrite under conditions that result in endogenous nitrosation is probably carcinogenic to humans (Group 2A). (L135)
Source: Toxin and Toxin Target Database (T3DB)
ICSC Safety Card
1041
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
A severe irritant to the eyes, skin & mucous membranes.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Degradant/impurity
Filler
Fragrance
No specific technical function
Preservative
Processing aids not otherwise specified
Softener and conditioner
Stabilizing agent
Regulatory List Membership (5)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Magnesium Nitrate.
Regulatory Flags
preservative
eu_children_restricted
epa_safer_alternative
ifra_fragrance
Known Synonyms
Nitric acid, magnesium salt (2:1)
UN 1474 (DOT)
Nitric acid, magnesium salt
EINECS 233-826-7
Magnesium(II) NItrate (1:2)
UNII-77CBG3UN78
Chemical Function
Preservative
Softener and conditioner
No specific technical function
Degradant/impurity
Fragrance
Processing aids not otherwise specified
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
CEDI
Indirect additives food contact (10/2018)
children; Europe; Personal care
children; Europe; Personal care - general moisturizing - hand/body lotion
children; Europe; Personal care - body hygiene - body wash
children; Europe; Personal care - hair styling and care - shampoo
children; Europe; Personal care - specialized bath products - bubble bath
Europe; Personal care
Europe; Personal care
SCIL (9/2019)
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3303299
Frequently Asked Questions
Is Magnesium Nitrate allowed in the EU?
Magnesium Nitrate EU regulatory status: permitted. Maximum allowed concentration: 0.0015%. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Nitrate do in cosmetics?
Magnesium Nitrate functions as: Hair conditioning agent; stabiliser in CMIT/MIT preservative systems. It is classified as a cosmetic ingredient in our database. CAS number: 10377-60-3.
Is Magnesium Nitrate used outside cosmetics?
Magnesium Nitrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Magnesium Nitrate have different safety status in cosmetics vs industrial chemicals?
Magnesium Nitrate is classified GHS Danger (H272, H315, H319, H335, H370, H372, H371) in the chemicals database but is allowed in EU cosmetics at max 0.0015%.
Compliance Tools
Check Magnesium Nitrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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