Is Locked Nucleic Acid-1 safe in cosmetics?
Locked Nucleic Acid-1 has a safety rating of "POOR" in our database. EU status: permitted. US status: restricted.
Poor
Cosmetic Ingredient
Locked Nucleic Acid-1
INCI: LOCKED NUCLEIC ACID-1
Locked Nucleic Acid-1 (CAS 206055-71-2 [^1_5]) is a cosmetic cosmetic ingredient functioning as Not established for cosmetic use (LNA-type nucleoside derivative; primarily. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 206055-71-2 [^1_5] →
Auto-generated CPSR Part A draft with source citations
Function
Not established for cosmetic use (LNA-type nucleoside derivative; primarily pharmaceutical/research)
Safety Rating
POOR
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Permitted — not specifically restricted under 21 CFR; falls under general cosmetic ingredient safety burden on manufacturer
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Locked Nucleic Acid-1.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Locked Nucleic Acid-1.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Locked Nucleic Acid-1 allowed in the EU?
Locked Nucleic Acid-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Locked Nucleic Acid-1 do in cosmetics?
Locked Nucleic Acid-1 functions as: Not established for cosmetic use (LNA-type nucleoside derivative; primarily pharmaceutical/research). It is classified as a cosmetic ingredient in our database. CAS number: 206055-71-2 [^1_5].
Compliance Tools
Check Locked Nucleic Acid-1 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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