Is Lactoscatone safe in cosmetics?
Lactoscatone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Lactoscatone
Also known as: 3,8a-Ethano-8aH-1-benzopyran-2(3H)-one, hexahydro-3,5,5-trimethyl-, Decahydro-2,8,8-trimethylnaphthalene-2,4a-carbolactone
INCI: LACTOSCATONE
Lactoscatone (CAS 21280-29-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 21280-29-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
5,5,8-trimethyl-10-oxatricyclo[6.2.2.01,6]dodecan-9-one
InChIKey
TUVXRDNMAFEUBI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted under 21 CFR 700; RIFM Expert Panel concluded safe under the limits described
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lactoscatone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Lactoscatone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
3,8a-Ethano-8aH-1-benzopyran-2(3H)-one, hexahydro-3,5,5-trimethyl-
Decahydro-2,8,8-trimethylnaphthalene-2,4a-carbolactone
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Lactoscatone allowed in the EU?
Lactoscatone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lactoscatone do in cosmetics?
Lactoscatone functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 21280-29-5.
Is Lactoscatone used outside cosmetics?
Lactoscatone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Lactoscatone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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