Is Kaempferol safe in cosmetics?
Kaempferol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Kaempferol
Kaempferol (CAS 520-18-3 (EC 208-287-6)) is a cosmetic cosmetic ingredient functioning as Antioxidant; Softener and conditioner. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 520-18-3 (EC 208-287-6) →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant; Softener and conditioner
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Kaempferol.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
acne
{"cas_number": "520-18-3", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory", "mechanism_of_action": "Bioactive compound, specialized mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "8-15", "clinical_study_duration_weeks": "12", "sample_size": "35", "double_blind": "No", "placebo_controlled": "Yes", "published_journal…
anti_pollution
{"cas_number": "520-18-3", "ingredient_class": "Nrf2_activator", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_k…
antioxidant
{"cas_number": "520-18-3", "antioxidant_class": "flavonoid", "chemical_subclass": "flavonol", "molecular_weight_daltons": "286.24", "orac_value_umol_te_per_g": "14200", "dpph_radical_scavenging_ic50_ug_per_ml": "11-20", "abts_trolox_equivalent": "not available", "singlet_oxygen_quenching": "not available", "superoxide_dismutase_mimetic": "not available", "hydroxyl_radical_scavenging": "not availab…
Expert Verdict
Expert safety assessment and concern-level summary for Kaempferol.
Regulatory Flags
endocrine_disruptor
Frequently Asked Questions
Is Kaempferol allowed in the EU?
Kaempferol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Kaempferol do in cosmetics?
Kaempferol functions as: Antioxidant; Softener and conditioner. It is classified as a cosmetic ingredient in our database. CAS number: 520-18-3 (EC 208-287-6).
Compliance Tools
Check Kaempferol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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