Also known as: EINECS 283-892-6, Indigofera tinctoria
INCI: INDIGOFERA TINCTORIA LEAF EXTRACT
Indigofera Tinctoria Leaf Extract (CAS 84775-63-3) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Hair Dyeing. Reported NOAEL =0.87 mg/kg bw in rat (SCCS_vision_codex); EU Regulation 1223/2009 status: restricted, max 25%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 84775-63-3 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Indigofera Tinctoria Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
10 study endpoints found for Indigofera Tinctoria Leaf Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.87 mg/kg bw | oral | rat | carcinogenicity | SCCS_vision_codex |
| NOAEL | =0.87 mg/kg bw | oral | rat | carcinogenicity | SCCS_vision_codex |
| NOAEL | =0.87 mg/kg bw | oral | rat | carcinogenicity | SCCS_vision_codex |
| NOAEL | =0.87 mg/kg bw | oral | rat | carcinogenicity | SCCS_vision_codex |
| NOAEL | =8.7 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =8.7 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =8.7 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =8.7 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =40 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =40 mg/kg bw | oral | rat | dermal absorption | SCCS_vision_codex |
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Expert safety assessment and concern-level summary for Indigofera Tinctoria Leaf Extract.
Public NOAEL study rows linked to Indigofera Tinctoria Leaf Extract by CAS number or substance name.
Indigofera Tinctoria Leaf Extract has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Indigofera Tinctoria Leaf Extract EU regulatory status: restricted. Maximum allowed concentration: 25%. This is based on EU Regulation 1223/2009 and its amendments.
Indigofera Tinctoria Leaf Extract functions as: Skin Conditioning, Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 84775-63-3.
The NOAEL (No Observed Adverse Effect Level) for Indigofera Tinctoria Leaf Extract is =0.87 mg/kg bw based on a carcinogenicity study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS_vision_codex.
Indigofera Tinctoria Leaf Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Check Indigofera Tinctoria Leaf Extract compliance across multiple jurisdictions:
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Indigofera Tinctoria Leaf Extract in your formulation.