What is the NOAEL for Indigofera tinctoria extract?
Indigofera tinctoria extract has 18 NOAEL studies in the database. The lowest reported value is 0.87 mg/kg bw via oral in rat. Source: SCCS_vision_codex.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Indigofera tinctoria extract
Also known as: EINECS 283-892-6, Indigofera tinctoria
CAS 84775-63-3
Indigofera tinctoria extract (CAS 84775-63-3) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.
View cosmetic safety profile for Indigofera Tinctoria Leaf Extract →
SOURCE
noael studies public
NOAEL studies
18
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
5 fields
Name
Indigofera tinctoria extract
CAS Number
84775-63-3
DTXSID
DTXSID501019805
Synonyms
EINECS 283-892-6Indigofera tinctoria
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
DeodorizerHumectantSoftener and conditionerNo specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.87 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.87 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.87 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.87 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =8.7 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =8.7 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =8.7 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =8.7 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =40 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =40 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =40 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =40 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| 0.87 | mg/kg bw | carcinogenicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 0.87 | mg/kg bw | dermal absorption | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 0.87 | mg/kg bw | dermal absorption | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 8.7 | mg/kg bw | dermal absorption | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =40 | mg/kg bw | dermal absorption | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =40 | mg/kg bw | dermal absorption | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
Showing 18 of 18 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Indigofera tinctoria, ext. | 283-892-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
SCCS Opinions
EU Scientific Committee opinions tied to the matched substance.
SOURCE
EU SCCS
1 opinions
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1615/20 | 3 April 2020 | safe | 25.0% | weak skin sensitisation potential |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
25%
Category
Plant Extract
Frequently Asked Questions
What regulatory lists include Indigofera tinctoria extract?
Indigofera tinctoria extract appears on 1 regulatory/inventory list including Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Indigofera tinctoria extract used in cosmetics?
Yes, Indigofera tinctoria extract is also indexed as a cosmetic ingredient under the name Indigofera Tinctoria Leaf Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Indigofera tinctoria extract come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Indigofera tinctoria extract used outside industrial chemicals?
Indigofera tinctoria extract also appears in cosmetics databases.