Is Hydroxyphenoxy Propionic Acid safe in cosmetics?
Hydroxyphenoxy Propionic Acid has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hydroxyphenoxy Propionic Acid
Also known as: UNII-WSI8A5QG10, (+)-2-(4-Hydroxyphenoxy)propionic acid, (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid, (R)-2-(p-Hydroxyphenoxy)propionic acid, D-2-(4-Hydroxyphenoxy)propionic acid (+3 more)
INCI: HYDROXYPHENOXY PROPIONIC ACID
Hydroxyphenoxy Propionic Acid (CAS 94050-90-5) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 94050-90-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Hydroxyphenoxy Propionic Acid is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2R)-2-(4-hydroxyphenoxy)propanoic acid
InChIKey
AQIHDXGKQHFBNW-ZCFIWIBFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific CFR restriction; no CIR review. Classified for R&D use only by some suppliers.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxyphenoxy Propionic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
Corrosive
Hazard Class and Category
Eye Dam. 1
Hazard Statements
- H318 Causes serious eye damage
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "brightening, antioxidant-protection", "mechanism_of_action": "Exfoliation, cell turnover acceleration, keratolytic", "target_skin_layer": "stratum corneum, epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "8-15", "clinical_study_duration_weeks": "12", "sample_size": "40", "double_blind": "No", "placebo_controlled": "Yes", "pub…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Hydroxyphenoxy Propionic Acid.
Known Synonyms
UNII-WSI8A5QG10
(+)-2-(4-Hydroxyphenoxy)propionic acid
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
(R)-2-(p-Hydroxyphenoxy)propionic acid
D-2-(4-Hydroxyphenoxy)propionic acid
Propanoic acid, 2-(4-hydroxyphenoxy)-, (2R)-
Propanoic acid, 2-(4-hydroxyphenoxy)-, (R)-
Radianskin PW LS
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Hydroxyphenoxy Propionic Acid allowed in the EU?
Hydroxyphenoxy Propionic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyphenoxy Propionic Acid do in cosmetics?
Hydroxyphenoxy Propionic Acid functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 94050-90-5.
Is Hydroxyphenoxy Propionic Acid used outside cosmetics?
Hydroxyphenoxy Propionic Acid also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Hydroxyphenoxy Propionic Acid have different safety status in cosmetics vs industrial chemicals?
Hydroxyphenoxy Propionic Acid is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Hydroxyphenoxy Propionic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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