Is Hydrolyzed Collagen safe in cosmetics?
Hydrolyzed Collagen has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Hydrolyzed Collagen
INCI: HYDROLYZED COLLAGEN
Hydrolyzed Collagen (CAS 9015-54-7) is a cosmetic cosmetic ingredient functioning as hair conditioning, moisture binding, film-forming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9015-54-7 →
Auto-generated CPSR Part A draft with source citations
Function
hair conditioning, moisture binding, film-forming
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR included in keratin-derived ingredients review; safe as used in cosmetic formulations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrolyzed Collagen.
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Hydrolyzed Collagen, relevant to systemic exposure and MoS calculations.
Absorption %
1-3%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
minimal
Topical Bioavailability
0.5-2%
Safety Margin Factor
low
Vehicle Dependent
Yes — absorption varies by formulation
Source: CIR
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| GCC | halal_prohibited | - | All cosmetics |
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Face Cream | 0.5–2 | 5 | CIR/VCRP |
| Conditioner | 0.5–2 | 5 | CIR/VCRP |
Additional Ingredient Properties
10 property records from structured ingredient metadata.
amino_acid
{"cas_number": "9064-67-9", "ingredient_class": "collagen_derivative", "source_origin": "animal", "molecular_weight_range_Da": "2000-5000", "amino_acid_composition_key": "glycine_proline_hydroxyproline_rich", "isoelectric_point": "5.0", "charge_at_pH_5_5": "zwitterionic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "excellent", "moisture_binding_capacity":…
anti_pollution
{"cas_number": "9007-34-5", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhibiti…
baby_pediatric
{"cas_number": "9015-54-7/68410-45-7", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "6", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Protein, film-forming", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Prot…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,dry,combination,normal,mature", "acne_safe": "yes", "source": "Humectant"}
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "5.0", "typical_concentration_pct": "3.0", "product_type": "Hair Conditioner", "function_at_concentration": "Conditioning", "source": "Supplier TDS"}
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "25", "estimated_cost_per_kg_usd_high": "45", "natural_premium_markup_pct": "35", "organic_certified_premium_pct": "65", "supply_chain_volatility": "medium", "primary_source_region": "France/US", "synthetic_vs_natural_cost_ratio": "2.0", "bulk_discount_threshold_kg": "100", "seasonal_price_variation": "medium", "commodity_or_specialty": "…
dermal_absorption
{"molecular_weight_da": "Variable", "skin_penetration_level": "surface", "penetration_depth": "stratum corneum", "absorption_pct": "1-3", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "yes", "skin_barrier_effect": "strengthens", "bioavailability_topical_pct": "0.5-2", "safety_margin_factor": "low", "source": "CIR"}
hair_care
{"hair_function": "protein-treatment", "hair_type_suitability": "medium/coarse", "curl_pattern_suitability": "all", "porosity_suitability": "high", "protein_sensitivity": "protein", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Humectant
Softener and conditioner
Thickening agent
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Hydrolyzed Collagen.
Regulatory Flags
cir-approved
moisture-binding
film-forming
protein-hydrolysate
animal-derived
vegan-note
cortex-penetration
fda_food_additive
Chemical Function
Softener and conditioner
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Hydrolyzed Collagen allowed in the EU?
Hydrolyzed Collagen EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrolyzed Collagen do in cosmetics?
Hydrolyzed Collagen functions as: hair conditioning, moisture binding, film-forming. It is classified as a cosmetic ingredient in our database. CAS number: 9015-54-7.
Compliance Tools
Check Hydrolyzed Collagen compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Collagen Amino Acids
Moderate
Chemical family
Humectant; Softener and conditioner
Desamido Collagen
Good
Chemical family
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