Is Hexyl Methacrylate safe in cosmetics?
Hexyl Methacrylate has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Hexyl Methacrylate
Also known as: 2-Propenoic acid, 2-methyl-, hexyl ester, EINECS 205-521-9, Hexyl 2-methyl-2-propenoate, Methacrylic acid, hexyl ester, NSC 24169 (+1 more)
INCI: HEXYL METHACRYLATE
Hexyl Methacrylate (CAS 142-09-6) is a cosmetic cosmetic ingredient functioning as Film former / monomer (primarily nail products, polymerised systems). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 142-09-6 →
Auto-generated CPSR Part A draft with source citations
Function
Film former / monomer (primarily nail products, polymerised systems)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
hexyl 2-methylprop-2-enoate
InChIKey
LNCPIMCVTKXXOY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not listed in 21 CFR 700 prohibited/restricted list
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyl Methacrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Methacrylates ... produce slight to moderate skin and eye irritation ... depending upon volatility, these materials also may be sensory irritants. /Methacrylic acid & derivatives/
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Indirect Food Contact Additives
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Hexyl Methacrylate.
Regulatory Flags
ifra_fragrance
Known Synonyms
2-Propenoic acid, 2-methyl-, hexyl ester
EINECS 205-521-9
Hexyl 2-methyl-2-propenoate
Methacrylic acid, hexyl ester
NSC 24169
UNII-538B2Q3HSV
Chemical Function
Fragrance
Regulatory Lists
Indirect additives food contact (10/2018)
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1422108
Frequently Asked Questions
Is Hexyl Methacrylate allowed in the EU?
Hexyl Methacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyl Methacrylate do in cosmetics?
Hexyl Methacrylate functions as: Film former / monomer (primarily nail products, polymerised systems). It is classified as a cosmetic ingredient in our database. CAS number: 142-09-6.
Is Hexyl Methacrylate used outside cosmetics?
Hexyl Methacrylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyl Methacrylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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