Is Hexanediol Dimethacrylate safe in cosmetics?
Hexanediol Dimethacrylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hexanediol Dimethacrylate
INCI: 1,6-HEXANEDIOL DIMETHACRYLATE
Hexanediol Dimethacrylate (CAS 6606-59-3) is a cosmetic cosmetic ingredient functioning as Crosslinking agent and film former, primarily used in dental and nail. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 6606-59-3 →
Auto-generated CPSR Part A draft with source citations
Function
Crosslinking agent and film former, primarily used in dental and nail applications
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
6-(2-methylprop-2-enoyloxy)hexyl 2-methylprop-2-enoate
InChIKey
SAPGBCWOQLHKKZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted with no specific 21 CFR restriction; FDA-cleared for dental devices
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexanediol Dimethacrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Monomers
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Hexanediol Dimethacrylate.
Regulatory Flags
potential-allergen
Chemical Function
Softener and conditioner
Monomers
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183323
Frequently Asked Questions
Is Hexanediol Dimethacrylate allowed in the EU?
Hexanediol Dimethacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexanediol Dimethacrylate do in cosmetics?
Hexanediol Dimethacrylate functions as: Crosslinking agent and film former, primarily used in dental and nail applications. It is classified as a cosmetic ingredient in our database. CAS number: 6606-59-3.
Is Hexanediol Dimethacrylate used outside cosmetics?
Hexanediol Dimethacrylate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexanediol Dimethacrylate compliance across multiple jurisdictions:
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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