What is the NOAEL for 1,6-Hexanediol dimethacrylate?
1,6-Hexanediol dimethacrylate has 5 NOAEL studies in the database. The lowest reported value is 14.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,6-Hexanediol dimethacrylate
Also known as: 2-Propenoic acid, 2-methyl-, 1,6-hexanediyl ester, 2-Propenoic acid, 2-methyl-, 1,1'-(1,6-hexanediyl) ester, EINECS 229-551-7
CAS 6606-59-3
1,6-Hexanediol dimethacrylate (CAS 6606-59-3) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Hexanediol Dimethacrylate →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
1,6-Hexanediol dimethacrylate
CAS Number
6606-59-3
DTXSID
DTXSID9044455
Molecular Formula
C14H22O4
InChI Key
SAPGBCWOQLHKKZ-UHFFFAOYSA-N
Monoisotopic Mass
254.151809
Synonyms
2-Propenoic acid, 2-methyl-, 1,6-hexanediyl ester2-Propenoic acid, 2-methyl-, 1,1'-(1,6-hexanediyl) esterEINECS 229-551-7
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Softener and conditionerMonomers
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =14.5 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| RAO49190JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RAO49190JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RAO49190JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RAO49190JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1,6-hexanediyl bismethacrylate | 229-551-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3183323
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 1,6-Hexanediol dimethacrylate used in cosmetics?
Yes, 1,6-Hexanediol dimethacrylate is also indexed as a cosmetic ingredient under the name Hexanediol Dimethacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,6-Hexanediol dimethacrylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,6-Hexanediol dimethacrylate used outside industrial chemicals?
1,6-Hexanediol dimethacrylate also appears in cosmetics, pharmaceutical databases.