Moderate Emollient NOAEL Data

Green Tea Extract (Camellia Sinensis Leaf Extract)

Also known as: Camellia sinensis extract, Camellia thea extract

INCI: GREEN TEA EXTRACT (CAMELLIA SINENSIS LEAF EXTRACT)

Green Tea Extract (Camellia Sinensis Leaf Extract) (CAS 84650-60-2) is a cosmetic emollient functioning as Emollient. Reported NOAEL =100 mg/kg/d (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 84650-60-2 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient
Safety Rating
MODERATE

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Active Ingredient. Not included

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Green Tea Extract (Camellia Sinensis Leaf Extract).

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

8 study endpoints found for Green Tea Extract (Camellia Sinensis Leaf Extract). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =100 mg/kg/d oral - oral toxicity CIR_vision_codex
NOAEL =100 mg/kg/d oral - oral toxicity CIR_vision_codex
NOAEL =100 mg/kg/d oral - oral toxicity CIR_vision_codex
NOAEL =100 mg/kg/d oral - oral toxicity CIR_vision_codex
NOAEL =200 mg/kg body weight oral - oral toxicity CIR_vision_codex
NOAEL =200 mg/kg body weight oral - oral toxicity CIR_vision_codex
NOAEL =200 mg/kg body weight oral - oral toxicity CIR_vision_codex
NOAEL =200 mg/kg body weight oral - oral toxicity CIR_vision_codex

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Astringent Biocide Bleaching agent Deodorizer Flavouring and nutrient Fragrance Humectant Pharmaceutical Softener and conditioner
Regulatory List Membership (3)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Green Tea Extract (Camellia Sinensis Leaf Extract).

Regulatory Flags

eu_children_restricted fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Green Tea Extract (Camellia Sinensis Leaf Extract) by CAS number or substance name.

Studies
8
Lowest NOAEL
100
Highest NOAEL
200

Units vary across source rows: mg/kg body weight, mg/kg/d

CIR_vision_codex

Known Synonyms

Camellia sinensis extract Camellia thea extract

Chemical Function

Humectant Softener and conditioner Biocide UV stabilizer Antioxidant Astringent Deodorizer

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - dental care - toothpaste Europe; Personal care Europe; Personal care Europe; Personal care food_additive; Substances Added to Food (formerly EAFUS) (2/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
sinecatechins
ChEMBL ID
CHEMBL1201723
View full pharmaceutical profile →

Frequently Asked Questions

Is Green Tea Extract (Camellia Sinensis Leaf Extract) safe in cosmetics?

Green Tea Extract (Camellia Sinensis Leaf Extract) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 8 toxicological study endpoint(s) are available in our database.

Is Green Tea Extract (Camellia Sinensis Leaf Extract) allowed in the EU?

Green Tea Extract (Camellia Sinensis Leaf Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Green Tea Extract (Camellia Sinensis Leaf Extract) do in cosmetics?

Green Tea Extract (Camellia Sinensis Leaf Extract) functions as: Emollient. It is classified as a Emollient in our database. CAS number: 84650-60-2.

What is the NOAEL for Green Tea Extract (Camellia Sinensis Leaf Extract)?

The NOAEL (No Observed Adverse Effect Level) for Green Tea Extract (Camellia Sinensis Leaf Extract) is =100 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: CIR_vision_codex.

Is Green Tea Extract (Camellia Sinensis Leaf Extract) used outside cosmetics?

Green Tea Extract (Camellia Sinensis Leaf Extract) also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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