Gotu Kola Extract

Also known as: gotu kola

INCI: CENTELLA ASIATICA EXTRACT

Gotu Kola Extract (CAS 84696-21-9) is a cosmetic active ingredient functioning as Skin conditioning, wound healing; TECA complex. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 84696-21-9 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, wound healing; TECA complex
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
283-640-5

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR Expert Panel (2023) concluded safe in present practices when formulated to be non-sensitizing. Max reported use 0.5% (face/neck). Oral reproductive toxicity in male rats does not translate to cosmetic exposure risk.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Gotu Kola Extract.

Calculate MoS for your specific formulation with the MoS Calculator.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Face Cream 0.1–2 5 CIR/VCRP
Serum 0.1–2 5 CIR/VCRP

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"cas_number": "84696-21-9", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "p_acnes_mic_ug_per_ml": ">2000", "sebum_reduction_pct_clinical": "0-5", "optimal_ph_for_efficacy": "5.0-7.0", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne"…
anti_aging
{"anti_aging_claim": "anti-wrinkle, barrier-repair, collagen-boosting", "mechanism_of_action": "Triterpenoids, madecassoside, asiaticoside stimulate collagen", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "12-20", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes",…
anti_pollution
{"cas_number": "84696-21-9", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modul…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,sensitive,combination,normal,acne-prone,rosacea", "acne_safe": "yes", "source": "Wound healing"}
concentration
{"min_concentration_pct": "0.5", "max_concentration_pct": "3.0", "typical_concentration_pct": "1.5", "product_type": "Toner", "function_at_concentration": "Soothing", "source": "Clinical literature"}
hair_care
{"hair_function": "scalp-care", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "kerati…
pediatric_safety
{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "5.0", "adult_max_concentration_pct": "5.0", "pediatric_dermal_absorption_factor": "normal", "diaper_area_safe": "yes", "pediatric_allergy_prevalence": "low", "banned_in_children_products_eu": "no", "banned…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "6.5", "stable_ph_min": "4.5", "stable_ph_max": "7.0", "degrades_above_ph": "7.5", "degrades_below_ph": "4.0", "ph_dependent_function": "Wound healing; stable moderate pH", "formulation_note": "Triterpenoids stable in acidic to neutral", "source": "Formulation literature"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Cleaning agent Humectant Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Gotu Kola Extract.

Regulatory Flags

cir-reviewed no-sccs-opinion weak-sensitizer-risk reproductive-toxicity-oral-high-dose low-dermal-absorption

Known Synonyms

gotu kola

Chemical Function

Antioxidant Humectant Softener and conditioner Cleaning agent

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Gotu Kola Extract safe in cosmetics?

Gotu Kola Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Gotu Kola Extract allowed in the EU?

Gotu Kola Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gotu Kola Extract do in cosmetics?

Gotu Kola Extract functions as: Skin conditioning, wound healing; TECA complex. It is classified as a Active Ingredient in our database. CAS number: 84696-21-9.

Is Gotu Kola Extract used outside cosmetics?

Gotu Kola Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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