Is Glycyrrhiza Glabra Root Extract safe in cosmetics?
Glycyrrhiza Glabra Root Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Glycyrrhiza Glabra Root Extract
INCI: GLYCYRRHIZA GLABRA ROOT EXTRACT
Glycyrrhiza Glabra Root Extract (CAS 84775-66-6) is a cosmetic active ingredient functioning as Skin brightening, anti-inflammatory, antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 84775-66-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin brightening, anti-inflammatory, antioxidant
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Cosmetic ingredient with no FDA concentration restrictions. Anti-redness claims permitted as structure-function claims.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycyrrhiza Glabra Root Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "brightening, anti-inflammatory", "mechanism_of_action": "Glabridin, liquiritin", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "8-15", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytotherapy Research, JOCD", "improv…
pregnancy_detail
{"pregnancy_safe": "yes", "breastfeeding_safe": "yes", "risk_category": "not-rated", "reason": "Licorice extract; safe topically; brightening", "source": "dermatology literature"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Bleaching agent
Fragrance
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Glycyrrhiza Glabra Root Extract.
Regulatory Flags
rosacea-safe
anti-inflammatory
anti-erythema
tyrosinase-inhibitor
claims-sensitive
Chemical Function
Softener and conditioner
Antioxidant
Humectant
Fragrance
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
2
Frequently Asked Questions
Is Glycyrrhiza Glabra Root Extract allowed in the EU?
Glycyrrhiza Glabra Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycyrrhiza Glabra Root Extract do in cosmetics?
Glycyrrhiza Glabra Root Extract functions as: Skin brightening, anti-inflammatory, antioxidant. It is classified as a Active Ingredient in our database. CAS number: 84775-66-6.
Is Glycyrrhiza Glabra Root Extract used outside cosmetics?
Glycyrrhiza Glabra Root Extract also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glycyrrhiza Glabra Root Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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