Is Glucan (Beta-Glucan) safe in cosmetics?
Glucan (Beta-Glucan) has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Glucan (Beta-Glucan)
INCI: BETA-GLUCAN
Glucan (Beta-Glucan) (CAS 9041-22-9; also 26874-89-5, 53238-80-7, 1439905-58-4 (depending on source/polymerization)) is a cosmetic cosmetic ingredient functioning as Skin conditioning, moisturizing, skin protectant, antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
9041-22-9; also 26874-89-5, 53238-80-7, 1439905-58-4 (depending on source/polymerization)
View industrial chemical safety profile →
Function
Skin conditioning, moisturizing, skin protectant, antioxidant
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted under FDA; no CIR final report as standalone ingredient; widely used in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glucan (Beta-Glucan).
Calculate MoS for your specific formulation with the MoS Calculator.
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Serum | 0.1–1 | 2 | CIR Safety Assessment |
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"cas_number": "9041-22-9", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
anti_aging
{"anti_aging_claim": "barrier-repair, anti-inflammatory, hydration-plumping", "mechanism_of_action": "Cofactor for enzymatic reactions, antioxidant activity", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "12", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", …
anti_pollution
{"cas_number": "9004-54-0", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhibiti…
humectant
{"cas_number": "9051-97-2", "ingredient_class": "humectant/polysaccharide", "molecular_weight_Da": "variable", "chemical_type": "polysaccharide", "water_binding_mechanism": "hydrogen_bonding/hygroscopic/film_forming", "water_holding_capacity_g_per_g": "0.6-1.0", "hygroscopicity_at_50_RH": "excellent", "hygroscopicity_at_80_RH": "excellent", "NMF_component": "no", "NMF_percentage_natural": "0", "TE…
microbiome_impact
{"microbiome_effect": "positive", "prebiotic": "yes", "probiotic_compatible": "yes", "preservative_effect_on_microbiome": "Prebiotic polysaccharide; immunomodulatory; supports beneficial bacteria", "gut_microbiome_risk": "low", "microbiome_recovery_time": "<2 days", "selective_antimicrobial": "no", "beneficial_bacteria_support": "S. epidermidis, Lactobacillus spp, Corynebacterium spp", "pathogen_i…
pediatric_safety
{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "5.0", "adult_max_concentration_pct": "5.0", "pediatric_dermal_absorption_factor": "normal", "diaper_area_safe": "yes", "pediatric_allergy_prevalence": "low", "banned_in_children_products_eu": "no", "banned…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "8.0", "stable_ph_min": "3.5", "stable_ph_max": "9.0", "degrades_above_ph": "10.0", "degrades_below_ph": "3.0", "ph_dependent_function": "Polysaccharide; immune modulation", "formulation_note": "Soothing and moisturizing", "source": "Formulation literature"}
polymer
{"cas_number": "9041-22-9", "ingredient_class": "film_former/moisture_retention", "polymer_type": "natural_polysaccharide", "chemical_backbone": "other", "molecular_weight_Da_range": "75000-600000", "ionic_character": "nonionic", "pH_viscosity_sensitivity": "moderate", "salt_tolerance": "moderate", "electrolyte_effect_on_viscosity": "moderate", "temperature_viscosity_sensitivity": "moderate", "fil…
Expert Verdict
Expert safety assessment and concern-level summary for Glucan (Beta-Glucan).
Frequently Asked Questions
Is Glucan (Beta-Glucan) allowed in the EU?
Glucan (Beta-Glucan) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glucan (Beta-Glucan) do in cosmetics?
Glucan (Beta-Glucan) functions as: Skin conditioning, moisturizing, skin protectant, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 9041-22-9; also 26874-89-5, 53238-80-7, 1439905-58-4 (depending on source/polymerization).
Compliance Tools
Check Glucan (Beta-Glucan) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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