Is Ginkgo Biloba Leaf Extract safe in cosmetics?
Ginkgo Biloba Leaf Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Ginkgo Biloba Leaf Extract
Also known as: Ginkgo biloba, ext., EINECS 289-896-4, UNII-19FUJ2C58T, Gingko biloba, Ginkgo leaf extract
INCI: GINKGO BILOBA LEAF EXTRACT
Ginkgo Biloba Leaf Extract (CAS 90045-36-6) is a cosmetic active ingredient functioning as Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.
View industrial chemical safety profile for CAS 90045-36-6 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restrictions identified for cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ginkgo Biloba Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
IARC Carcinogenicity
International Agency for Research on Cancer (WHO) monograph evaluation.
IARC Group
2B
Volume
108
Evaluation Year
2013
Additional Ingredient Properties
5 property records from structured ingredient metadata.
acne
{"cas_number": "90045-36-6", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restrictio…
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-wrinkle", "mechanism_of_action": "Flavonoids, terpenoids, free radical scavenging", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "5-12", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phyto…
anti_pollution
{"cas_number": "90045-36-6", "ingredient_class": "antioxidant_pollution_shield/anti_smog", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5/UV_A/ozone/oxidative_stress", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "yes", "lipid_peroxidation_inhibition_pct": "75-…
depigmentation
{"cas_number": "90045-36-6", "ingredient_class": "combined_mechanism", "primary_mechanism_of_action": "Botanical extract with tyrosinase inhibition and/or antioxidant properties", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction_pct_c…
self_tanning
{"cas_number": "90045-36-6", "ingredient_class": "tan_extender", "tanning_mechanism": "other", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_formation_conc…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Biocide
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Ginkgo Biloba Leaf Extract.
Known Synonyms
Ginkgo biloba, ext.
EINECS 289-896-4
UNII-19FUJ2C58T
Gingko biloba
Ginkgo leaf extract
Chemical Function
Biocide
Antioxidant
Humectant
Deodorizer
Softener and conditioner
Flavouring and nutrient
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Ginkgo biloba extract
Food Category
preservative
Frequently Asked Questions
Is Ginkgo Biloba Leaf Extract allowed in the EU?
Ginkgo Biloba Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ginkgo Biloba Leaf Extract do in cosmetics?
Ginkgo Biloba Leaf Extract functions as: Antioxidant. It is classified as a Active Ingredient in our database. CAS number: 90045-36-6.
Is Ginkgo Biloba Leaf Extract used outside cosmetics?
Ginkgo Biloba Leaf Extract also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ginkgo Biloba Leaf Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
ALTHAEA ROSEA FLOWER EXTRACT
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Chemical family
Skin Conditioning
Althaea Rosea Extract
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Althaea Rosea Root Extract
Good
Chemical family
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