Is Geranyl Isobutyrate safe in cosmetics?
Geranyl Isobutyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Geranyl Isobutyrate
Also known as: trans-3-7-Dimethyl-2,6-octadienyl isobutyrate, 3,7-Dimethyl-2,6-octadienyl isobutyrate, (E)-, 3,7-Dimethyl-2,6-octadien-1-yl isobutyrate, trans-, 3,7-Dimethyl-2,6-octadien-1-yl 2-methylpropanoate, trans-, 3,7-Dimethyl-2,6-octadienyl 2-methylpropanoate, (E)- (+8 more)
INCI: GERANYL ISOBUTYRATE
Geranyl Isobutyrate (CAS 2345-26-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (perfuming); flavor agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2345-26-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient (perfuming); flavor agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(2E)-3,7-dimethylocta-2,6-dienyl] 2-methylpropanoate
InChIKey
OGJYXQFXLSCKTP-UKTHLTGXSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FDA 21 CFR 172.515; FEMA GRAS 2513
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Geranyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6480 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
72
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
GERANYL ISOBUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/64 | FAS 40-JECFA 49/329
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Geranyl Isobutyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
trans-3-7-Dimethyl-2,6-octadienyl isobutyrate
3,7-Dimethyl-2,6-octadienyl isobutyrate, (E)-
3,7-Dimethyl-2,6-octadien-1-yl isobutyrate, trans-
3,7-Dimethyl-2,6-octadien-1-yl 2-methylpropanoate, trans-
3,7-Dimethyl-2,6-octadienyl 2-methylpropanoate, (E)-
EINECS 219-062-7
FEMA No. 2513
Geranyl 2-methylpropanoate
Isobutyric acid, 3,7-dimethyl-2,6-octadienyl ester, trans-
Isobutyric acid, 3,7-dimethyl-2,6-octadienyl ester, (E)-
2,6-Octadien-1-ol, 3,7-dimethyl-, isobutyrate, trans-
Propanoic acid, 2-methyl-, 3,7-dimethyl-2,6-octadienyl ester,
UNII-P6D2F72907
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Geranyl Isobutyrate allowed in the EU?
Geranyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Geranyl Isobutyrate do in cosmetics?
Geranyl Isobutyrate functions as: Fragrance ingredient (perfuming); flavor agent. It is classified as a cosmetic ingredient in our database. CAS number: 2345-26-8.
Is Geranyl Isobutyrate used outside cosmetics?
Geranyl Isobutyrate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Geranyl Isobutyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Good
Chemical family
Perfuming
GERANYL LINALOOL
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