Is Gastrodin safe in cosmetics?
Gastrodin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Gastrodin
Also known as: 4-(Hydroxymethyl)phenyl β-D-glucopyranoside, Gastrodine
INCI: GASTRODIN
Gastrodin (CAS 62499-27-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning; skin lightening active (tyrosinase inhibitor). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 62499-27-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; skin lightening active (tyrosinase inhibitor)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
InChIKey
PUQSUZTXKPLAPR-UJPOAAIJSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; FDA UNII: 5YS9U2W3RQ
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Gastrodin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Gastrodin.
Known Synonyms
4-(Hydroxymethyl)phenyl β-D-glucopyranoside
Gastrodine
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GASTRODIN
ChEMBL ID
CHEMBL274739
Frequently Asked Questions
Is Gastrodin allowed in the EU?
Gastrodin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Gastrodin do in cosmetics?
Gastrodin functions as: Skin conditioning; skin lightening active (tyrosinase inhibitor). It is classified as a cosmetic ingredient in our database. CAS number: 62499-27-8.
Is Gastrodin used outside cosmetics?
Gastrodin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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