Excellent Cosmetic Ingredient Dermal Penetration

Galactose

INCI: GALACTOSE

Galactose (CAS 59-23-4 (D-galactose)) is a cosmetic cosmetic ingredient functioning as Humectant, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 59-23-4 (D-galactose) →

Auto-generated CPSR Part A draft with source citations
CAS Number
59-23-4 (D-galactose)
View industrial chemical safety profile →
Function
Humectant, skin conditioning
Safety Rating
EXCELLENT

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted — naturally occurring monosaccharide; not restricted under 21 CFR

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Galactose.

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Galactose, relevant to systemic exposure and MoS calculations.

Absorption %
1-3%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
180.2 Da
Log P
-2.9
Systemic Absorption
minimal
Topical Bioavailability
0.5-2%
Safety Margin Factor
low

Source: Cosmetic Science

Additional Ingredient Properties

5 property records from structured ingredient metadata.

acne
{"cas_number": "59-23-4", "anti_acne_mechanism": "keratolytic", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "non_inflammatory", "sebum_reduction_pct_clinical": "0-5", "keratolytic_strength": "mild", "exfoliation_mechanism": "chemical", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", …
anti_aging
{"anti_aging_claim": "hydration-plumping", "mechanism_of_action": "Humectant, water binding, barrier support", "target_skin_layer": "stratum corneum, epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "5-10", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "JDD, Int J Cosm…
dermal_absorption
{"molecular_weight_da": "180.2", "log_p_value": "-2.9", "skin_penetration_level": "surface", "penetration_depth": "stratum corneum", "absorption_pct": "1-3", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0.5-2", "safety_margin_factor": "low", "source": "Cosmetic …
exfoliant
{"cas_number": "59-23-4", "ingredient_class": "PHA", "chemical_subclass": "polyhydroxy_acid", "molecular_weight_Da": "180.16", "pH_dependent_activity": "minimal", "penetration_depth": "stratum_corneum", "mechanism_of_action": "enzyme_activation", "onset_of_action": "days", "peak_effect_timeline": "12-16 weeks", "cell_turnover_increase_pct": "5-10%", "TEWL_effect": "neutral", "comedolytic": "no", "…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …

Expert Verdict

Expert safety assessment and concern-level summary for Galactose.

Frequently Asked Questions

Is Galactose safe in cosmetics?

Galactose has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Galactose allowed in the EU?

Galactose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Galactose do in cosmetics?

Galactose functions as: Humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 59-23-4 (D-galactose).

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